What happens to cancer cells after they're killed by treatments?
Cancer treatments like chemotherapy kill tumor cells, for example, by pushing them to self-destruct, shrivel up and quietly die in a process called apoptosis, or less commonly, by triggering a more explosive form of cell death called necroptosis. But what happens to those cancer cells after they've been slain? When cancer cells meet their demise, their membranes usually become compromised , as occurs in apoptosis , a form of programmed cell death that removes unneeded or damaged cells from the body. Once the molecular switches that trigger apoptosis are flipped "on," the dying cell shrinks and bits of its membrane break away in "blebs." This causes the cells' internal components to leak out and attract phagocytes, or immune cells responsible for ingesting cellular debris. The summoned phagocytes engulf the dead cancer cells and then break them down into smaller components, such as sugars and nucleic acids, chain-like molecules found in DNA. Via this pr...